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Eunjung Lee, Lihua Liu, Juanjuan Zhang, ie Hwang, Andre Elizabeth. Kim, Ann S. Hamilton, Anna H. Wu, Dennis Deapen; Tummy Cancer tumors Difference among Korean People in america by Tumor Features: Research that have Non-Latina Whites, Japanese People in america, Southern area Koreans, and you can Japanese. Cancer tumors Epidemiol Biography; twenty-six (4): 587–596.
Conceptual
Background: Tummy malignant tumors chance shows good racial-ethnic difference in the united states, that have Korean Us citizens feeling definitely the greatest incidence. I checked stomach disease occurrence trends in Korean Us citizens because of the tumefaction subsite, histology, and you can stage and compared these with incidence rates during the racial-cultural groups on the next highest price (Japanese Us americans) and also the reduced price (non-Latina whites; NHWs) plus populations within the Southern area Korea and you can The japanese.
Methods: We computed years-modified frequency pricing of the racial-ethnic groups, sex, and tumefaction properties, with the 1988–2012 Ca Disease Registry analysis. Study to your Southern area Korea and you can The japanese have been extracted from the newest literature or other information.
Results: Between 1988 and you will 2012 in the Ca, Korean People in the us had from the five times better frequency than NHWs and you will twice that Japanese People in the us. Tumefaction properties differed from the cultural class and you can intercourse. The fresh new frequency in Korean Americans provides denied through the the past few years, for cardia and you may noncardia internet and one another abdominal- and you can diffuse-kind of histology. In the event Korean Us citizens was indeed recognized in the an early on stage than other Californians, this new proportion having local disease (43%) are much smaller compared to within the Southern area Korea (57%), in which people-dependent assessment can be obtained.
Conclusions: Stomach cancer tumors incidence refused on the higher exposure cultural communities. Yet not, brand new chronic disparity between Korean People in the us and other racial-cultural groups warrants extra methods for reduction and you will earlier prognosis.
Impact: Research from California Cancer tumors Registry research identified a beneficial racial-ethnic subgroup that have belly disease disparity that will make use of focused protection hot or not przeglД…d and you may testing efforts. Cancer tumors Epidemiol Biography AACR.
Addition
Stomach malignant tumors was a normally fatal situation that have an effective 5-season cousin success speed out of lower than 29% features big influence on quality of life with the thriving customers (1). In the event belly cancers occurrence has diminished significantly for the past numerous ages in the us, of eleven.eight each a hundred,100 inside 1975 so you can 7.0 each 100,100 in 2012 (1), a substantial disparity inside the belly cancers weight is seen across the racial cultural organizations (2–4). Korean American individuals still have definitely the fresh new higher stomach cancers chance of all the racial/ethnic teams (2–4), which have an effective 4- so you’re able to 5-bend large occurrence than simply low-Latina whites (NHW) inside 2003–2008 (5). Unlike the significant reduced total of tummy cancer tumors incidence in all almost every other racial/ethnic communities, including Far-eastern American subgroups such as for example Chinese, Japanese, and you may Vietnamese for which belly cancers is amongst the most useful 5 cancers, this new incidence when you look at the Korean Us citizens don’t rather (3). So it disparity parallels the brand new higher occurrence from inside the Southern Korea. Southern area Korea contains the highest stomach cancers price international (regarding 10 times of the occurrence when you look at the You.S. whites), followed closely by Japan (6). While the incidence for the The japanese has actually diminished substantially in the recent decades (5, 7), the fresh new chance for the Southern area Korea features reduced little (8, 9).
Etiology away from belly cancer can disagree because of the tumefaction subsite (cardia versus. noncardia) and you can histology (intestinal compared to. diffuse-type; ref. 10). Cardia gastric disease try associated with being obese and you will reflux condition, whereas noncardia gastric cancer are on the Helicobacter pylori disease (10). Abdominal variety of is primarily with the H. pylori issues combined with ecological things instance salt or other losing weight products, while diffuse sorts of is assumed are about H. pylori and you can genetic circumstances (11–14). These subsite- and you will histology-established belly cancer subtypes demonstrate some other occurrence trends and you can racial difference. Such as, compared to the nice reduction of overall belly cancers occurrence in all cultural groups in the usa, the brand new frequency away from cardia malignant tumors improved certainly one of males involving the 70s and you may 1980s (15, 16), plus the incidence of diffuse-sorts of stomach malignant tumors enhanced anywhere between 1973 and you will 2000 inside people and females, whites and nonwhites (15, 17). Incidence pricing of most subtypes was in fact large inside nonwhites compared to whites, except for high incidence regarding cardia subtype inside the whites (fifteen, 16). Considering the differential etiology and you will epidemiology across the subtypes and you can competition groups (10), it’s important to view the brand new chance trend and you may cultural difference because of the cyst subtype and stage in the analysis so you can package effective prevention measures. However, such as suggestions wasn’t discussed erican subgroups.
